PATENT COOPERATION TREATY PCT INTERNATIONAL SEARCH REPORT (PCT Article 18 and Rules 43 and 44) Applicant’s or agent’s file reference International application No. FOR FURTHER ACTION see Form PCT/ISA/220 as well as, where applicable, item 5 below. International filing date (day/month/year) (Earliest) Priority Date (day/month/year) Applicant This international search report has been prepared by this International Searching Authority and is transmitted to the applicant according to Article 18. A copy is being transmitted to the International Bureau. This international search report consists of a total of _______ sheets. It is also accompanied by a copy of each prior art document cited in this report. 1. Basis of the report a. With regard to the language, the international search was carried out on the basis of: the international application in the language in which it was filed. a translation of the international application into _____________________________ which is the language of a translation furnished for the purposes of international search (Rules 12.3(a) and 23.1(b)). b. This international search report has been established taking into account the rectification of an obvious mistake authorized by or notified to this Authority under Rule 91 (Rule 43.6bis(a)). c. With regard to any nucleotide and/or amino acid sequence disclosed in the international application, see Box No. I. 2. Certain claims were found unsearchable (see Box No. II). 3. Unity of invention is lacking (see Box No. III). 4. With regard to the title, the text is approved as submitted by the applicant. the text has been established by this Authority to read as follows: 5. With regard to the abstract, the text is approved as submitted by the applicant. the text has been established, according to Rule 38.2, by this Authority as it appears in Box No. IV. The applicant may, within one month from the date of mailing of this international search report, submit comments to this Authority. 6. With regard to the drawings, a. the figure of the drawings to be published with the abstract is Figure No. ____________ as suggested by the applicant. as selected by this Authority, because the applicant failed to suggest a figure. as selected by this Authority, because this figure better characterizes the invention. b. none of the figures is to be published with the abstract. Form PCT/ISA/210 (first sheet) (July 2009) American LegalNet, Inc. www.FormsWorkFlow.com INTERNATIONAL SEARCH REPORT Box No. I International application No. Nucleotide and/or amino acid sequence(s) (Continuation of item 1.c of the first sheet) 1. With regard to any nucleotide and/or amino acid sequence disclosed in the international application, the international search was carried out on the basis of a sequence listing filed or furnished: a. (means) on paper in electronic form b. (time) in the international application as filed together with the international application in electronic form subsequently to this Authority for the purposes of search 2. In addition, in the case that more than one version or copy of a sequence listing has been filed or furnished, the required statements that the information in the subsequent or additional copies is identical to that in the application as filed or does not go beyond the application as filed, as appropriate, were furnished. 3. Additional comments: Form PCT/ISA/210 (continuation of first sheet (1)) (July 2009) American LegalNet, Inc. www.FormsWorkFlow.com INTERNATIONAL SEARCH REPORT Box No. II International application No. Observations where certain claims were found unsearchable (Continuation of item 2 of first sheet) This international search report has not been established in respect of certain claims under Article 17(2)(a) for the following reasons: 1. Claims Nos.: because they relate to subject matter not required to be searched by this Authority, namely: 2. Claims Nos.: because they relate to parts of the international application that do not comply with the prescribed requirements to such an extent that no meaningful international search can be carried out, specifically: 3. Claims Nos.: because they are dependent claims and are not drafted in accordance with the second and third sentences of Rule 6.4(a). Box No. III Observations where unity of invention is lacking (Continuation of item 3 of first sheet) This International Searching Authority found multiple inventions in this international application, as follows: 1. As all required additional search fees were timely paid by the applicant, this international search report covers all searchable claims. 2. As all searchable claims could be searched without effort justifying additional fees, this Authority did not invite payment of additional fees. 3. As only some of the required additional search fees were timely paid by the applicant, this international search report covers only those claims for which fees were paid, specifically claims Nos.: 4. No required additional search fees were timely paid by the applicant. Consequently, this international search report is restricted to the invention first mentioned in the claims; it is covered by claims Nos.: Remark on Protest The additional search fees were accompanied by the applicant’s protest and, where applicable, the payment of a protest fee. The additional search fees were accompanied by the applicant’s protest but the applicable protest fee was not paid within the time limit specified in the invitation. No protest accompanied the payment of additional search fees. Form PCT/ISA/210 (continuation of first sheet (2)) (July 2009) American LegalNet, Inc. www.FormsWorkFlow.com INTERNATIONAL SEARCH REPORT Box No. IV International application No. Text of the abstract (Continuation of item 5 of the first sheet) Form PCT/ISA/210 (continuation of first sheet (3)) (July 2009) American LegalNet, Inc. www.FormsWorkFlow.com INTERNATIONAL SEARCH REPORT A. International application No. CLASSIFICATION OF SUBJECT MATTER According to International Patent Classification (IPC) or to both national classification and IPC B. FIELDS SEARCHED Minimum documentation searched (classification system followed by classification symbols) Documentation searched other than minimum documentation to the extent that such documents are included in the fields searched Electronic data base consulted during the international search (name of data base and, where practicable, search terms used) C. DOCUMENTS CONSIDERED TO BE RELEVANT Category* Citation of document, with indication, where appropriate, of the relevant passages Further documents are listed in the continuation of Box C. Relevant to claim No. See patent family annex. * Special categories of cited documents: “A” document defining the general state of the art which is not considered to be of particular relevance “E” earlier application or patent but published on or after the international filing date “L” document which may throw doubts on priority claim(s) or which is cited to establish the publication date of another citation or other special reason (as specified) “O” document referring to an oral disclosure, use, exhibition or other means “P” document published prior to the international filing date but later than the priority date claimed “T” later document published after the international filing date or priority date and not in conflict with the application but cited to understand the principle or theory underlying the invention Date of the actual completion of the international search Date of mailing of the international search report Name and mailing address of the ISA/ Authorized officer Facsimile No. Telephone No. Form PCT/ISA/210 (second sheet) (July 2009) “X” document of particular relevance; the claimed invention cannot be considered novel or cannot be considered to involve an inventive step when the document is taken alone “Y” document of particular relevance; the claimed invention cannot be considered to involve an inventive step when the document is combined with one or more other such documents, such combination being obvious to a person skilled in the art “&” document member of the same patent family American LegalNet, Inc. www.FormsWorkFlow.com INTERNATIONAL SEARCH REPORT C (Continuation). Category* International application No. DOCUMENTS CONSIDERED TO BE RELEVANT Citation of document, with indication, where appropriate, of the relevant passages Relevant to claim No. Form PCT/ISA/210 (continuation of second sheet) (July 2009) American LegalNet, Inc. www.FormsWorkFlow.com INTERNATIONAL SEARCH REPORT Information on patent family members International application No. Form PCT/ISA/210 (patent family annex) (July 2009) American LegalNet, Inc. www.FormsWorkFlow.com INTERNATIONAL SEARCH REPORT International application No. Form PCT/ISA/210 (extra sheet) (July 2009) American LegalNet, Inc. www.FormsWorkFlow.com